Isolation of a Coronavirus from Kidney Biopsies of Endemic Balkan Nephropathy Patients
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چکیده
منابع مشابه
Endemic (Balkan) nephropathy is aristolochic acid nephropathy.
Endemic nephropathy is a syndrome that comprises two entities: chronic interstitial nephropathy and urothelial cell cancers predominantly of the upper urinary tract. The etiological agent for the disease is aristolochic acid, a compound found in the plants of Aristolochia spp. The development of urothelial cancers is characterized by the formation of aristolactam DNA adducts leading to mutation...
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Introduction Balkan endemic nephropathy (BEN) is a chronic irreversible interstitial sclerosis, for which over the last 25 years, chronic exposure to aristolochic acid from the contaminated cereal seeds has been considered the most likely cause. The aim of our research is to reevaluate trends of disease and to try to obtain new information about practical implementing of in-field screening of B...
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RENAL INTERSTITIAL FIBROSIS IS A MAJOR FEATURE OF BALKAN ENDEMIC NEPHROPATHY (BEN) G. A. Müller, M. Zeisberg, F Strutz Dept. of Nephrology & Rheumatology, Georg-August Universität Göttingen, 37075 Göttingen, Germany Balkan Nephropathy is a common renal disease in the Balkan region which often leads to endstage renal failure. The pathogenesis of this disease is still unknown, however, the pathwa...
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The correlation between the geographic occurrence of Balkan endemic nephropathy (BEN) and low rank Pliocene lignites is striking. Comparison of mass spectra of methanol extracts from lignite samples collected in the vicinity of two endemic villages, with mass spectra of methanol extracts higher grade coals, shows the presence of many more potentially nephrotoxic compounds, and much higher total...
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The aim of the paper was to summarize the results of autopsy studies of end-stage Balkan endemic nephropathy (BEN), to compare the results of our biopsy studies of earlier stages with those of other research groups and to discuss the issue of the most up-to-date hypothesis about the pathogenesis of this still enigmatic disease. Our experiences have been based on light microscopic examination of...
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ژورنال
عنوان ژورنال: Nephron
سال: 1999
ISSN: 1660-8151,2235-3186
DOI: 10.1159/000045269